Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes

BACKGROUND: National Comprehensive Cancer Network (NCCN) recently recommended germline genetic testing for all pancreatic cancer patients. However, the genes targeted by genetic testing and the feasibility of selecting patients likely to carry pathogenic variants have not been sufficiently verified....

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Detalles Bibliográficos
Autores principales: Mizukami, Keijiro, Iwasaki, Yusuke, Kawakami, Eiryo, Hirata, Makoto, Kamatani, Yoichiro, Matsuda, Koichi, Endo, Mikiko, Sugano, Kokichi, Yoshida, Teruhiko, Murakami, Yoshinori, Nakagawa, Hidewaki, Spurdle, Amanda B., Momozawa, Yukihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519363/
https://www.ncbi.nlm.nih.gov/pubmed/32980694
http://dx.doi.org/10.1016/j.ebiom.2020.103033

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