Synthesis, molecular docking, antiplasmodial and antioxidant activities of new sulfonamido-pepetide derivatives

Twenty-three new series of toluene-sulfonamide dipeptide derivatives were synthesized and screened for antiplasmodial and antioxidant potencies. Many of the derivatives were active against Plasmodium falciparum with IC(50) ranging from 3.20 – 9.10 μM. The ability of compounds 7h, 7m and 7n (IC(50) o...

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Detalles Bibliográficos
Autores principales: Onoabedje, Efeturi A., Ibezim, Akachukwu, Okoro, Uchechukwu C., Batra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519377/
https://www.ncbi.nlm.nih.gov/pubmed/33005786
http://dx.doi.org/10.1016/j.heliyon.2020.e04958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519377/
https://www.ncbi.nlm.nih.gov/pubmed/33005786
http://dx.doi.org/10.1016/j.heliyon.2020.e04958

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