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Synthesis, molecular docking, antiplasmodial and antioxidant activities of new sulfonamido-pepetide derivatives
Twenty-three new series of toluene-sulfonamide dipeptide derivatives were synthesized and screened for antiplasmodial and antioxidant potencies. Many of the derivatives were active against Plasmodium falciparum with IC(50) ranging from 3.20 – 9.10 μM. The ability of compounds 7h, 7m and 7n (IC(50) o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519377/ https://www.ncbi.nlm.nih.gov/pubmed/33005786 http://dx.doi.org/10.1016/j.heliyon.2020.e04958 |