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Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes

BACKGROUND: While mutations in the cardiac type 2 ryanodine receptor (RyR2) have been linked to exercise-induced or catecholaminergic polymorphic ventricular tachycardia (CPVT), its association with polymorphic ventricular tachycardia (PMVT) occurring at rest is unclear. We aimed at constructing a p...

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Detalles Bibliográficos
Autores principales:	Sleiman, Yvonne, Souidi, Monia, Kumar, Ritu, Yang, Ellen, Jaffré, Fabrice, Zhou, Ting, Bernardin, Albin, Reiken, Steve, Cazorla, Olivier, Kajava, Andrey V., Moreau, Adrien, Pasquié, Jean-Luc, Marks, Andrew R., Lerman, Bruce B., Chen, Shuibing, Cheung, Jim W., Evans, Todd, Lacampagne, Alain, Meli, Albano C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519379/ https://www.ncbi.nlm.nih.gov/pubmed/32980690 http://dx.doi.org/10.1016/j.ebiom.2020.103024

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