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Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism
Through advanced mechanistic modeling and the generation of large high-quality datasets, machine learning is becoming an integral part of understanding and engineering living systems. Here we show that mechanistic and machine learning models can be combined to enable accurate genotype-to-phenotype p...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519671/ https://www.ncbi.nlm.nih.gov/pubmed/32978375 http://dx.doi.org/10.1038/s41467-020-17910-1 |