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Severity assessment in mice subjected to carbon tetrachloride
The Directive 2010/63 EU requires classifying burden and severity in all procedures using laboratory animals. This study evaluated the severity of liver fibrosis induction by intraperitoneal carbon tetrachloride (CCl(4)) injections in mice. 29 male C57BL/6N mice were treated three times per week for...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519684/ https://www.ncbi.nlm.nih.gov/pubmed/32978437 http://dx.doi.org/10.1038/s41598-020-72801-1 |