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Severity assessment in mice subjected to carbon tetrachloride

The Directive 2010/63 EU requires classifying burden and severity in all procedures using laboratory animals. This study evaluated the severity of liver fibrosis induction by intraperitoneal carbon tetrachloride (CCl(4)) injections in mice. 29 male C57BL/6N mice were treated three times per week for...

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Detalles Bibliográficos
Autores principales:	Ernst, Lisa, Zieglowski, Leonie, Schulz, Mareike, Moss, Michaela, Meyer, Marco, Weiskirchen, Ralf, Palme, Rupert, Hamann, Melanie, Talbot, Steven R., Tolba, René H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519684/ https://www.ncbi.nlm.nih.gov/pubmed/32978437 http://dx.doi.org/10.1038/s41598-020-72801-1

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