Eculizumab treatment for renal failure in a pediatric patient with COVID-19

While there are increasing reports of acute kidney injury among hospitalized adults with COVID-19, there is still limited information on renal complications associated with COVID-19 in children. The cause of kidney involvement in COVID-19 is likely multifactorial, and appears to involve a complex pr...

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Detalles Bibliográficos
Autores principales: Mahajan, Ruchi, Lipton, Marissa, Broglie, Larisa, Jain, Namrata Gargee, Uy, Natalie Somera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519698/
https://www.ncbi.nlm.nih.gov/pubmed/32981025
http://dx.doi.org/10.1007/s40620-020-00858-2
Descripción
Sumario:While there are increasing reports of acute kidney injury among hospitalized adults with COVID-19, there is still limited information on renal complications associated with COVID-19 in children. The cause of kidney involvement in COVID-19 is likely multifactorial, and appears to involve a complex process, including complement dysregulation and thrombotic microangiopathy. We present a pediatric case of COVID-19 and renal failure due to thombotic microangiopathy, successfully treated with eculizumab.

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