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Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group()
BACKGROUND: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease. MATERIAL AND METHODS: We...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier España, S.L.U.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519708/ https://www.ncbi.nlm.nih.gov/pubmed/33015369 http://dx.doi.org/10.1016/j.medcle.2020.06.013 |
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author | Zalba Marcos, Saioa Antelo, María Luisa Galbete, Arkaitz Etayo, Maialen Ongay, Eva García-Erce, José Antonio |
author_facet | Zalba Marcos, Saioa Antelo, María Luisa Galbete, Arkaitz Etayo, Maialen Ongay, Eva García-Erce, José Antonio |
author_sort | Zalba Marcos, Saioa |
collection | PubMed |
description | BACKGROUND: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease. MATERIAL AND METHODS: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution. RESULTS: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units. CONCLUSION: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results. |
format | Online Article Text |
id | pubmed-7519708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Published by Elsevier España, S.L.U. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75197082020-09-28 Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() Zalba Marcos, Saioa Antelo, María Luisa Galbete, Arkaitz Etayo, Maialen Ongay, Eva García-Erce, José Antonio Med Clin (Engl Ed) Brief Report BACKGROUND: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease. MATERIAL AND METHODS: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution. RESULTS: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units. CONCLUSION: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results. Published by Elsevier España, S.L.U. 2020-10-23 2020-09-26 /pmc/articles/PMC7519708/ /pubmed/33015369 http://dx.doi.org/10.1016/j.medcle.2020.06.013 Text en © 2020 Published by Elsevier España, S.L.U. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Brief Report Zalba Marcos, Saioa Antelo, María Luisa Galbete, Arkaitz Etayo, Maialen Ongay, Eva García-Erce, José Antonio Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title | Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title_full | Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title_fullStr | Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title_full_unstemmed | Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title_short | Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group() |
title_sort | infection and thrombosis associated with covid-19: possible role of the abo blood group() |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519708/ https://www.ncbi.nlm.nih.gov/pubmed/33015369 http://dx.doi.org/10.1016/j.medcle.2020.06.013 |
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