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Fractional order epidemic model for the dynamics of novel COVID-19
To curtail and control the pandemic coronavirus (Covid-19) epidemic, there is an urgent need to understand the transmissibility of the infection. Mathematical model is an important tool to describe the transmission dynamics of any disease. In this research paper, we present a mathematical model cons...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519730/ http://dx.doi.org/10.1016/j.aej.2020.09.029 |
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author | Abdullahi Baba, Isa Ahmad Nasidi, Bashir |
author_facet | Abdullahi Baba, Isa Ahmad Nasidi, Bashir |
author_sort | Abdullahi Baba, Isa |
collection | PubMed |
description | To curtail and control the pandemic coronavirus (Covid-19) epidemic, there is an urgent need to understand the transmissibility of the infection. Mathematical model is an important tool to describe the transmission dynamics of any disease. In this research paper, we present a mathematical model consisting of a system of nonlinear fractional order differential equations, in which bats were considered as the origin of the virus that spread the disease into human population. We proved the existence and uniqueness of the solution of the model by applying Banach contraction mapping principle. The equilibrium solutions (disease free & endemic) of the model were found to be locally asymptotically stable. The key parameter (Basic reproduction number) describing the number of secondary infections was obtained. Furthermore, global stability analysis of the solutions was carried out using Lyapunov candidate function. We performed numerical simulation, which shows the changes that occur at every time instant due to the variation of [Formula: see text]. From the graphs, we can see that FODEs have rich dynamics and are better descriptors of biological systems than traditional integer – order models. |
format | Online Article Text |
id | pubmed-7519730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. |
record_format | MEDLINE/PubMed |
spelling | pubmed-75197302020-09-28 Fractional order epidemic model for the dynamics of novel COVID-19 Abdullahi Baba, Isa Ahmad Nasidi, Bashir Alexandria Engineering Journal Article To curtail and control the pandemic coronavirus (Covid-19) epidemic, there is an urgent need to understand the transmissibility of the infection. Mathematical model is an important tool to describe the transmission dynamics of any disease. In this research paper, we present a mathematical model consisting of a system of nonlinear fractional order differential equations, in which bats were considered as the origin of the virus that spread the disease into human population. We proved the existence and uniqueness of the solution of the model by applying Banach contraction mapping principle. The equilibrium solutions (disease free & endemic) of the model were found to be locally asymptotically stable. The key parameter (Basic reproduction number) describing the number of secondary infections was obtained. Furthermore, global stability analysis of the solutions was carried out using Lyapunov candidate function. We performed numerical simulation, which shows the changes that occur at every time instant due to the variation of [Formula: see text]. From the graphs, we can see that FODEs have rich dynamics and are better descriptors of biological systems than traditional integer – order models. The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. 2021-02 2020-09-26 /pmc/articles/PMC7519730/ http://dx.doi.org/10.1016/j.aej.2020.09.029 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of Faculty of Engineering, Alexandria University. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Abdullahi Baba, Isa Ahmad Nasidi, Bashir Fractional order epidemic model for the dynamics of novel COVID-19 |
title | Fractional order epidemic model for the dynamics of novel COVID-19 |
title_full | Fractional order epidemic model for the dynamics of novel COVID-19 |
title_fullStr | Fractional order epidemic model for the dynamics of novel COVID-19 |
title_full_unstemmed | Fractional order epidemic model for the dynamics of novel COVID-19 |
title_short | Fractional order epidemic model for the dynamics of novel COVID-19 |
title_sort | fractional order epidemic model for the dynamics of novel covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519730/ http://dx.doi.org/10.1016/j.aej.2020.09.029 |
work_keys_str_mv | AT abdullahibabaisa fractionalorderepidemicmodelforthedynamicsofnovelcovid19 AT ahmadnasidibashir fractionalorderepidemicmodelforthedynamicsofnovelcovid19 |