Cargando…

Pancréas ectopique de localisation hépatique

Ectopic pancreas (or aberrant or pancreatic heterotopia) is defined as pancreatic tissue outside the boundaries of the pancreas, without anatomic connection to the main gland. Its incidence is between 0.5% and 14% in autopsy series, but it is probably underestimated because it is often asymptomatic....

Descripción completa

Detalles Bibliográficos
Autor principal: Limaïem, Faten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519799/
https://www.ncbi.nlm.nih.gov/pubmed/33014246
http://dx.doi.org/10.11604/pamj.2020.36.250.21309
_version_ 1783587644346728448
author Limaïem, Faten
author_facet Limaïem, Faten
author_sort Limaïem, Faten
collection PubMed
description Ectopic pancreas (or aberrant or pancreatic heterotopia) is defined as pancreatic tissue outside the boundaries of the pancreas, without anatomic connection to the main gland. Its incidence is between 0.5% and 14% in autopsy series, but it is probably underestimated because it is often asymptomatic. It most commonly affects the duodenum (30-35%), the stomach (30%), and the jejunum (15%). Hepatic involvement is exceptional. We here report a new case of unexpected detection. The study involved a 54-year-old, hypertense female patient who had undergone surgery for adenocarcinoma of the sigmoid classified pT3N1b (A) two years before. Disease progression was marked by the occurrence of multiple predominant secondary nodules in the right hepatic lobe (B). Neoadjuvant chemotherapy (4 cicles of FOLFOX-ERBITUX) was started. The patient received right lobectomy. The histological examination of the different surgical specimens confirmed the presence of secondary, moderately differentiated hepatic adenocarcinoma of colorectal origin with healthy surgical excision margins. The surrounding liver was the site of unsystematized macrovacuolar steatosis in 20% of cases. It was associated with a focus of pancreatic heterotopia, including some acini and excretory canals arranged in lobules (C, D). The postoperative course was simple; however, patient’s outcome was marked by recurrence of cancer in the left lobe of the liver.
format Online
Article
Text
id pubmed-7519799
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-75197992020-10-02 Pancréas ectopique de localisation hépatique Limaïem, Faten Pan Afr Med J Images in Clinical Medicine Ectopic pancreas (or aberrant or pancreatic heterotopia) is defined as pancreatic tissue outside the boundaries of the pancreas, without anatomic connection to the main gland. Its incidence is between 0.5% and 14% in autopsy series, but it is probably underestimated because it is often asymptomatic. It most commonly affects the duodenum (30-35%), the stomach (30%), and the jejunum (15%). Hepatic involvement is exceptional. We here report a new case of unexpected detection. The study involved a 54-year-old, hypertense female patient who had undergone surgery for adenocarcinoma of the sigmoid classified pT3N1b (A) two years before. Disease progression was marked by the occurrence of multiple predominant secondary nodules in the right hepatic lobe (B). Neoadjuvant chemotherapy (4 cicles of FOLFOX-ERBITUX) was started. The patient received right lobectomy. The histological examination of the different surgical specimens confirmed the presence of secondary, moderately differentiated hepatic adenocarcinoma of colorectal origin with healthy surgical excision margins. The surrounding liver was the site of unsystematized macrovacuolar steatosis in 20% of cases. It was associated with a focus of pancreatic heterotopia, including some acini and excretory canals arranged in lobules (C, D). The postoperative course was simple; however, patient’s outcome was marked by recurrence of cancer in the left lobe of the liver. The African Field Epidemiology Network 2020-08-06 /pmc/articles/PMC7519799/ /pubmed/33014246 http://dx.doi.org/10.11604/pamj.2020.36.250.21309 Text en Copyright: Faten Limaïem et al. https://creativecommons.org/licenses/by/4.0 The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Images in Clinical Medicine
Limaïem, Faten
Pancréas ectopique de localisation hépatique
title Pancréas ectopique de localisation hépatique
title_full Pancréas ectopique de localisation hépatique
title_fullStr Pancréas ectopique de localisation hépatique
title_full_unstemmed Pancréas ectopique de localisation hépatique
title_short Pancréas ectopique de localisation hépatique
title_sort pancréas ectopique de localisation hépatique
topic Images in Clinical Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519799/
https://www.ncbi.nlm.nih.gov/pubmed/33014246
http://dx.doi.org/10.11604/pamj.2020.36.250.21309
work_keys_str_mv AT limaiemfaten pancreasectopiquedelocalisationhepatique