Cargando…

Effects of Co-Administration of Icariin and Panax notoginseng Saponins on Intestinal Microbiota and Hippocampal Protein Expression in a Mouse Model of Alzheimer’s Disease

OBJECTIVE: We investigated the effect of icariin (ICA) combined with Panax notoginseng saponins (PNS) on intestinal microbiota and hippocampal protein expression in amyloid precursor protein/presenilin 1 (APP/PS1) transgenic mice, a model of Alzheimer’s disease (AD). METHODS: Transgenic mice were tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ting, Dong, Keli, Xiao, Lan, Li, Guangcheng, Zhang, Zhanwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519864/ https://www.ncbi.nlm.nih.gov/pubmed/33061388 http://dx.doi.org/10.2147/NDT.S253972

Ejemplares similares

Yizhijiannao Granule and a combination of its effective monomers, icariin and Panax notoginseng saponins, inhibit early PC12 cell apoptosis induced by beta-amyloid (25–35)☆
por: Zhang, Ting, et al.
Publicado: (2012)

Saponin accumulation in the seedling root of Panax notoginseng
por: Wang, Dong, et al.
Publicado: (2011)

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
por: Peng, Ming, et al.
Publicado: (2018)

New dammarane-type triterpenoid saponins from Panax notoginseng saponins
por: Li, Qian, et al.
Publicado: (2020)

Pustular drug eruption due to Panax notoginseng saponins
por: Yin, ZhiQiang, et al.
Publicado: (2014)

Dammarane-type saponins from steamed leaves of Panax Notoginseng
por: Liu, Qing, et al.
Publicado: (2011)

Metabolomes and transcriptomes revealed the saponin distribution in root tissues of Panax quinquefolius and Panax notoginseng
por: Wei, Guangfei, et al.
Publicado: (2020)

High-throughput transcriptional profiling of perturbations by Panax ginseng saponins and Panax notoginseng saponins using TCM-seq
por: Cheng, Junyun, et al.
Publicado: (2023)

Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins
por: Feng, Hanzhou, et al.
Publicado: (2011)

Dammarane-type Triterpene Saponins from the Flowers of Panax notoginseng
por: Wang, Jing-Rong, et al.
Publicado: (2009)

Identification of Differentially Expressed Profiles of Alzheimer's Disease Associated Circular RNAs in a Panax Notoginseng Saponins-Treated Alzheimer's Disease Mouse Model
por: Huang, Jin-Lan, et al.
Publicado: (2018)

Panax Notoginseng Saponins Prevent Bone Loss by Promoting Angiogenesis in an Osteoporotic Mouse Model
por: Hu, Hao, et al.
Publicado: (2020)

Integrated metabolomic and transcriptomic analyses revealed the distribution of saponins in Panax notoginseng
por: Wei, Guangfei, et al.
Publicado: (2018)

Exploring the Mechanism of Panax notoginseng Saponins against Alzheimer's Disease by Network Pharmacology and Experimental Validation
por: Jiang, Yixuan, et al.
Publicado: (2021)

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells
por: Sun, Zongxi, et al.
Publicado: (2018)

Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss
por: Zhang, Xuelian, et al.
Publicado: (2021)

Panax notoginseng saponins and their applications in nervous system disorders: a narrative review
por: Qu, Jing, et al.
Publicado: (2020)

Chemical transformation and target preparation of saponins in stems and leaves of Panax notoginseng
por: Wang, Ru-Feng, et al.
Publicado: (2018)

Effects of Panax Notoginseng Saponins on Esterases Responsible for Aspirin Hydrolysis In Vitro
por: Sun, Zongxi, et al.
Publicado: (2018)

Structure and Location Studies on Key Enzymes in Saponins Biosynthesis of Panax notoginseng
por: Xia, Pengguo, et al.
Publicado: (2019)

Pharmacological Effect of Panax notoginseng Saponins on Cerebral Ischemia in Animal Models
por: Dong, Chao, et al.
Publicado: (2022)

Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation
por: Zhang, Chenyang, et al.
Publicado: (2022)

Anaphylactic Rare Saponins Separated from Panax notoginseng Saponin and a Proteomic Approach to Their Anaphylactic Mechanism
por: Hao, Feiran, et al.
Publicado: (2022)

Quantitative Comparison and Metabolite Profiling of Saponins in Different Parts of the Root of Panax notoginseng
por: Wang, Jing-Rong, et al.
Publicado: (2014)

Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease
por: Xu, Yu, et al.
Publicado: (2021)

Therapeutic effects of Panax notoginseng saponins in rheumatoid arthritis: network pharmacology and experimental validation
por: Ma, Xinnan, et al.
Publicado: (2023)

High nitrogen inhibits biomass and saponins accumulation in a medicinal plant Panax notoginseng
por: Cun, Zhu, et al.
Publicado: (2023)

Personalized bioconversion of Panax notoginseng saponins mediated by gut microbiota between two different diet-pattern healthy subjects
por: Wang, Li, et al.
Publicado: (2021)

Anti-Inflammatory Activity of Panax notoginseng Flower Saponins Quantified Using LC/MS/MS
por: Liu, Junchen, et al.
Publicado: (2023)

DPYSL2 is a novel regulator for neural stem cell differentiation in rats: revealed by Panax notoginseng saponin administration
por: Xiong, Liu-Lin, et al.
Publicado: (2020)

Panax notoginseng saponin attenuates hypoxia/reoxygenation-induced oxidative stress in cortical neurons★
por: Yan, Chen, et al.
Publicado: (2012)

Panax notoginseng Saponins for Treating Coronary Artery Disease: A Functional and Mechanistic Overview
por: Duan, Lian, et al.
Publicado: (2017)

Panax notoginseng saponins alleviate osteoporosis and joint destruction in rabbits with antigen-induced arthritis
por: Wei, Chen Chao, et al.
Publicado: (2021)

A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke
por: Wang, Cong, et al.
Publicado: (2021)

Physicochemical, Digestive, and Sensory Properties of Panax Notoginseng Saponins Encapsulated by Polymerized Whey Protein
por: Zhou, Zengjia, et al.
Publicado: (2021)

Suitable soil moisture contents for water use efficiency and saponins accumulation in Panax notoginseng
por: Zheng, Yu-jie, et al.
Publicado: (2021)

Integrated Chemical and Transcriptomic Analysis Reveals the Distribution of Protopanaxadiol- and Protopanaxatriol-Type Saponins in Panax notoginseng
por: Wei, Guangfei, et al.
Publicado: (2018)

Neuroprotective Properties of Panax notoginseng Saponins via Preventing Oxidative Stress Injury in SAMP8 Mice
por: Huang, Jin-Lan, et al.
Publicado: (2017)

Panax notoginseng saponins alleviate damage to the intestinal barrier and regulate levels of intestinal microbes in a rat model of chronic kidney disease
por: Xie, Jing, et al.
Publicado: (2022)

Stem-leaf saponins from Panax notoginseng counteract aberrant autophagy and apoptosis in hippocampal neurons of mice with cognitive impairment induced by sleep deprivation
por: Cao, Yin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2arce9aar82qsgtovfcpdvsddv