Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation

Glaucoma is a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs), the output neurons of the retina. Multiple lines of evidence show the endothelin (EDN, also known as ET) system is important in glaucomatous neurodegeneration. To date, the molecular mechanisms within RGC...

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Detalles Bibliográficos
Autores principales: Marola, Olivia J., Syc-Mazurek, Stephanie B., Howell, Gareth R., Libby, Richard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519907/
https://www.ncbi.nlm.nih.gov/pubmed/32980857
http://dx.doi.org/10.1038/s41419-020-02990-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519907/
https://www.ncbi.nlm.nih.gov/pubmed/32980857
http://dx.doi.org/10.1038/s41419-020-02990-0

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