Effect of PKC/NF-κB on the Regulation of P2X(3) Receptor in Dorsal Root Ganglion in Rats with Sciatic Nerve Injury

BACKGROUND: Protein kinase C (PKC), nuclear factor-kappa B p65 (NF-κB p65), and P2X(3) receptor (P2X(3)R) play significant roles in the sensitization and transduction of nociceptive signals, which are considered as potential targets for the treatment of neuropathic pain. However, the mechanisms and...

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Detalles Bibliográficos
Autores principales: Li, Xue, Yuan, Jie, Yu, Xuan, Zhang, Qin, Qin, Bangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519985/
https://www.ncbi.nlm.nih.gov/pubmed/33014214
http://dx.doi.org/10.1155/2020/7104392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519985/
https://www.ncbi.nlm.nih.gov/pubmed/33014214
http://dx.doi.org/10.1155/2020/7104392

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