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Effect of PKC/NF-κB on the Regulation of P2X(3) Receptor in Dorsal Root Ganglion in Rats with Sciatic Nerve Injury
BACKGROUND: Protein kinase C (PKC), nuclear factor-kappa B p65 (NF-κB p65), and P2X(3) receptor (P2X(3)R) play significant roles in the sensitization and transduction of nociceptive signals, which are considered as potential targets for the treatment of neuropathic pain. However, the mechanisms and...
Autores principales: | Li, Xue, Yuan, Jie, Yu, Xuan, Zhang, Qin, Qin, Bangyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519985/ https://www.ncbi.nlm.nih.gov/pubmed/33014214 http://dx.doi.org/10.1155/2020/7104392 |
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