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Lowest observed adverse effect level of pulmonary pathological alterations due to nitrous acid exposure in guinea pigs
BACKGROUND: We previously demonstrated that continuous exposure to nitrous acid gas (HONO) for 4 weeks, at a concentration of 3.6 parts per million (ppm), induced pulmonary emphysema-like alterations in guinea pigs. In addition, we found that HONO affected asthma symptoms, based on the measurement o...
Autores principales: | Ohyama, Masayuki, Nishimura, Hiroshi, Azuma, Kenichi, Minejima, Chika, Takenaka, Norimichi, Adachi, Shuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520026/ https://www.ncbi.nlm.nih.gov/pubmed/32979924 http://dx.doi.org/10.1186/s12199-020-00895-0 |
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