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Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies

CD47 belongs to immunoglobulin superfamily and is widely expressed on the surface of cell membrane, while another transmembrane protein SIRPα is restricted to the surface of macrophages, dendritic cells, and nerve cells. As a cell surface receptor and ligand, respectively, CD47 and SIRPα interact to...

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Detalles Bibliográficos
Autores principales: Lu, Quansheng, Chen, Xi, Wang, Shan, Lu, Yu, Yang, Chunsheng, Jiang, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520119/
https://www.ncbi.nlm.nih.gov/pubmed/33061420
http://dx.doi.org/10.2147/OTT.S249822