Cargando…
Apatinib attenuates phenotypic switching of arterial smooth muscle cells in vascular remodelling by targeting the PDGF Receptor‐β
Apatinib (YN968D1) is a small‐molecule tyrosine kinase inhibitor(TKI)which can inhibit the activity of vascular endothelial growth factor receptor‐2 (VEGFR‐2). It has been reported that apatinib has anti‐tumour effect of inhibiting proliferation and inducing apoptosis of a variety of solid tumour ce...
Autores principales: | Shao, Wenchao, Li, Xiaoguang, Peng, Jiangtong, Fan, Siyuan, Liang, Minglu, Huang, Kai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520274/ https://www.ncbi.nlm.nih.gov/pubmed/32697395 http://dx.doi.org/10.1111/jcmm.15623 |
Ejemplares similares
-
SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling
por: Xu, Yue, et al.
Publicado: (2023) -
Tanshinone II A attenuates vascular remodeling through klf4 mediated smooth muscle cell phenotypic switching
por: Lou, Guanhua, et al.
Publicado: (2020) -
Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling
por: Jain, Manish, et al.
Publicado: (2021) -
MiR-26a contributes to the PDGF-BB-induced phenotypic switch of vascular smooth muscle cells by suppressing Smad1
por: Yang, Xiaoyan, et al.
Publicado: (2017) -
Nucleolin promotes Ang II‐induced phenotypic transformation of vascular smooth muscle cells by regulating EGF and PDGF‐BB
por: Fang, Li, et al.
Publicado: (2020)