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UVA influenced the SIRT1‐miR‐27a‐5p‐SMAD2‐MMP1/COL1/BCL2 axis in human skin primary fibroblasts

Both SIRT1 and UVA radiation are involved in cellular damage processes such as apoptosis, senescence and ageing. MicroRNAs (miRNAs) have been reported to be closely related to UV radiation, as well as to SIRT1. In this study, we investigated the connections among SIRT1, UVA and miRNA in human skin p...

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Detalles Bibliográficos
Autores principales: Jiang, Shi‐Bin, Lu, Yan‐Song, Liu, Tao, Li, Liang‐Man, Wang, He‐Xiao, Wu, Yan, Gao, Xing‐Hua, Chen, Hong‐duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520305/
https://www.ncbi.nlm.nih.gov/pubmed/32790210
http://dx.doi.org/10.1111/jcmm.15610