Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway

Tubulointerstitial inflammation is crucial for the progression of diabetic nephropathy (DN), and tubular cells act as a driving force in the inflammatory cascade. Emerging data suggested that tacrolimus (TAC) ameliorates podocyte injury and macrophage infiltration in streptozotocin (STZ) mice. Howev...

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Detalles Bibliográficos
Autores principales: Zhang, Shumin, Wang, Huafen, Liu, Yifei, Yang, Wenxia, Liu, Jialu, Han, Yuzhang, Liu, Yu, Liu, Fuyou, Sun, Lin, Xiao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520323/
https://www.ncbi.nlm.nih.gov/pubmed/32779844
http://dx.doi.org/10.1111/jcmm.15562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520323/
https://www.ncbi.nlm.nih.gov/pubmed/32779844
http://dx.doi.org/10.1111/jcmm.15562

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