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A model-based analysis identifies differences in phenotypic resistance between in vitro and in vivo: implications for translational medicine within tuberculosis
Proper characterization of drug effects on Mycobacterium tuberculosis relies on the characterization of phenotypically resistant bacteria to correctly establish exposure–response relationships. The aim of this work was to evaluate the potential difference in phenotypic resistance in in vitro compare...
Autores principales: | Clewe, Oskar, Faraj, Alan, Hu, Yanmin, Coates, Anthony R. M., Simonsson, Ulrika S. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520421/ https://www.ncbi.nlm.nih.gov/pubmed/32488575 http://dx.doi.org/10.1007/s10928-020-09694-0 |
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