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Current treatment of COVID-19 in renal patients: hope or hype?

To date the severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), known as COVID-19, is for clinicians the most difficult global therapeutic problem. In this landscape, the management of patients with chronic kidney disease, acute kidney injury or patients undergoing immunosuppressant thera...

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Autores principales: Roberto, Palumbo, Francesco, Londrino, Emanuela, Cordova, Giorgia, Gambardella, Pasquale, Niscola, Sara, Dominijanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520511/
https://www.ncbi.nlm.nih.gov/pubmed/32986137
http://dx.doi.org/10.1007/s11739-020-02510-0
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author Roberto, Palumbo
Francesco, Londrino
Emanuela, Cordova
Giorgia, Gambardella
Pasquale, Niscola
Sara, Dominijanni
author_facet Roberto, Palumbo
Francesco, Londrino
Emanuela, Cordova
Giorgia, Gambardella
Pasquale, Niscola
Sara, Dominijanni
author_sort Roberto, Palumbo
collection PubMed
description To date the severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), known as COVID-19, is for clinicians the most difficult global therapeutic problem. In this landscape, the management of patients with chronic kidney disease, acute kidney injury or patients undergoing immunosuppressant therapies for kidney transplant or glomerular diseases, represent a clinical challenge for nephrologists, especially in patients with severe acute lung involvement. Therefore in this setting, due to the lack of anti-COVID treatment schedules, tailored management is mandatory to reduce the side effects, as consequence of impaired renal function and drugs interactions. We report the main treatment actually used against SARS-CoV-2, underlining its possible use in the nephropatic patients and the central role of nephrologists to improve the clinical outcome.
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spelling pubmed-75205112020-09-28 Current treatment of COVID-19 in renal patients: hope or hype? Roberto, Palumbo Francesco, Londrino Emanuela, Cordova Giorgia, Gambardella Pasquale, Niscola Sara, Dominijanni Intern Emerg Med Im - Review To date the severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2), known as COVID-19, is for clinicians the most difficult global therapeutic problem. In this landscape, the management of patients with chronic kidney disease, acute kidney injury or patients undergoing immunosuppressant therapies for kidney transplant or glomerular diseases, represent a clinical challenge for nephrologists, especially in patients with severe acute lung involvement. Therefore in this setting, due to the lack of anti-COVID treatment schedules, tailored management is mandatory to reduce the side effects, as consequence of impaired renal function and drugs interactions. We report the main treatment actually used against SARS-CoV-2, underlining its possible use in the nephropatic patients and the central role of nephrologists to improve the clinical outcome. Springer International Publishing 2020-09-28 2020 /pmc/articles/PMC7520511/ /pubmed/32986137 http://dx.doi.org/10.1007/s11739-020-02510-0 Text en © Società Italiana di Medicina Interna (SIMI) 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Im - Review
Roberto, Palumbo
Francesco, Londrino
Emanuela, Cordova
Giorgia, Gambardella
Pasquale, Niscola
Sara, Dominijanni
Current treatment of COVID-19 in renal patients: hope or hype?
title Current treatment of COVID-19 in renal patients: hope or hype?
title_full Current treatment of COVID-19 in renal patients: hope or hype?
title_fullStr Current treatment of COVID-19 in renal patients: hope or hype?
title_full_unstemmed Current treatment of COVID-19 in renal patients: hope or hype?
title_short Current treatment of COVID-19 in renal patients: hope or hype?
title_sort current treatment of covid-19 in renal patients: hope or hype?
topic Im - Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520511/
https://www.ncbi.nlm.nih.gov/pubmed/32986137
http://dx.doi.org/10.1007/s11739-020-02510-0
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