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Mechanisms of TERT Reactivation and Its Interaction with BRAF(V600E)
The telomerase reverse transcriptase (TERT) gene, which is repressed in most differentiated human cells, can be reactivated by somatic TERT alterations and epigenetic modulations. Moreover, the recruitment, accessibility, and binding of transcription factors also affect the regulation of TERT expres...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Endocrine Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520576/ https://www.ncbi.nlm.nih.gov/pubmed/32981294 http://dx.doi.org/10.3803/EnM.2020.304 |