Cargando…
DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions
R-loops are three-stranded structures consisting of a DNA/RNA hybrid and a displaced DNA strand. The regulatory factors required to process this fundamental genetic structure near double-strand DNA breaks (DSBs) are not well understood. We previously reported that cellular depletion of the ATP-depen...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520851/ https://www.ncbi.nlm.nih.gov/pubmed/33015627 http://dx.doi.org/10.1093/narcan/zcaa028 |