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Gut Bacterial Species Distinctively Impact Host Purine Metabolites during Aging in Drosophila
Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product of purine metabolism, is increased during aging in a m...
Autores principales: | Yamauchi, Toshitaka, Oi, Ayano, Kosakamoto, Hina, Akuzawa-Tokita, Yoriko, Murakami, Takumi, Mori, Hiroshi, Miura, Masayuki, Obata, Fumiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520893/ https://www.ncbi.nlm.nih.gov/pubmed/32916085 http://dx.doi.org/10.1016/j.isci.2020.101477 |
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