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Functional signatures of evolutionarily young CTCF binding sites

BACKGROUND: The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism and functional impact of evolutionarily novel CTCF binding sites are not yet fully...

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Detalles Bibliográficos
Autores principales:	Azazi, Dhoyazan, Mudge, Jonathan M., Odom, Duncan T., Flicek, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520972/ https://www.ncbi.nlm.nih.gov/pubmed/32988407 http://dx.doi.org/10.1186/s12915-020-00863-8

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