Overexpression of P‐glycoprotein and resistance to Imatinib in chronic myeloid leukemia patients

BACKGROUND: The P‐glycoprotein (P‐gp) is one of the mechanisms of Imatinib (IM) resistance in chronic myeloid leukemia (CML). P‐gp has been identified as an efflux pump involved in releasing of IM outside CML cells. To date, the P‐gp involvement in the IM resistance development was not completely un...

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Detalles Bibliográficos
Autores principales: Ammar, Mariam, Louati, Nour, Frikha, Imen, Medhaffar, Moez, Ghozzi, Hanen, Elloumi, Moez, Menif, Hela, Zeghal, Khaled, Ben Mahmoud, Lobna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521244/
https://www.ncbi.nlm.nih.gov/pubmed/32715517
http://dx.doi.org/10.1002/jcla.23374

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