Cargando…

SRXN1 stimulates hepatocellular carcinoma tumorigenesis and metastasis through modulating ROS/p65/BTG2 signalling

Sulfiredoxin 1 (SRXN1) is a pivotal regulator of the antioxidant response in eukaryotic cells. However, the role of SRXN1 in hepatocellular carcinoma (HCC) is far from clear. The present study aims to elucidate whether SRXN1 participates in tumorigenesis and metastasis of HCC and to determine the mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Xiufang, Yu, Hailing, Zhang, Qianqian, Huang, Quanyong, Hong, Xiaopeng, Yu, Ting, Lan, Huimin, Mei, Chaoming, Zhang, Wenkai, Luo, Hui, Pang, Pengfei, Shan, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521256/ https://www.ncbi.nlm.nih.gov/pubmed/32746503 http://dx.doi.org/10.1111/jcmm.15693

Ejemplares similares

SSR2 overexpression associates with tumorigenesis and metastasis of Hepatocellular Carcinoma through modulating EMT
por: Hong, Xiaopeng, et al.
Publicado: (2020)

Association of SRXN1 Receptor Gene Polymorphism with Susceptibility to Periodontitis
por: Murthykumar, Karthikeyan, et al.
Publicado: (2022)

Antioxidative stress protein SRXN1 can be used as a radiotherapy prognostic marker for prostate cancer
por: Wang, Xing, et al.
Publicado: (2023)

Emerging role of antiproliferative protein BTG1 and BTG2
por: Kim, Sang Hyeon, et al.
Publicado: (2022)

Tumor suppressors BTG1 and BTG2: Beyond growth control
por: Yuniati, Laurensia, et al.
Publicado: (2018)

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton
por: Tijchon, Esther, et al.
Publicado: (2015)

CircABCA13 acts as a miR‐4429 sponge to facilitate esophageal squamous cell carcinoma development by stabilizing SRXN1
por: Luo, Junwen, et al.
Publicado: (2023)

Beyond Antioxidant Activity: Redox Properties of Catechins May Affect Changes in the DNA Methylation Profile—The Example of SRXN1 Gene
por: Jakubek, Patrycja, et al.
Publicado: (2023)

The roles of BTG1 mRNA expression in cancers: A bioinformatics analysis
por: Zheng, Hua-chuan, et al.
Publicado: (2022)

TINCR inhibits the proliferation and invasion of laryngeal squamous cell carcinoma by regulating miR-210/BTG2
por: He, Guoqing, et al.
Publicado: (2021)

The interplay between autophagy and ROS in tumorigenesis
por: Kongara, Sameera, et al.
Publicado: (2012)

Identification of SRXN1 and KRT6A as Key Genes in Smoking-Related Non-Small-Cell Lung Cancer Through Bioinformatics and Functional Analyses
por: Zhou, Jiazhen, et al.
Publicado: (2022)

BTG Interacts with Retinoblastoma to Control Cell Fate in Dictyostelium
por: Conte, Daniele, et al.
Publicado: (2010)

Circular RNA circ_0014717 Suppresses Hepatocellular Carcinoma Tumorigenesis Through Regulating miR-668-3p/BTG2 Axis
por: Ma, Hongxi, et al.
Publicado: (2021)

Gene amplification‐driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A‐YTHDF2‐dependent in lung adenocarcinoma
por: Zhang, Chang, et al.
Publicado: (2022)

Btg2 Promotes Focal Segmental Glomerulosclerosis via Smad3‐Dependent Podocyte‐Mesenchymal Transition
por: Dan Hu, Qiong‐, et al.
Publicado: (2023)

Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study
por: Kunnas, Tarja, et al.
Publicado: (2016)

MiR-6875-3p promotes the proliferation, invasion and metastasis of hepatocellular carcinoma via BTG2/FAK/Akt pathway
por: Xie, Yingjun, et al.
Publicado: (2019)

BTG1 Expression Correlates with the Pathogenesis and Progression of Ovarian Carcinomas
por: Zhao, Yang, et al.
Publicado: (2013)

BTG1 inhibits malignancy as a novel prognosis signature in endometrial carcinoma
por: Li, Yibing, et al.
Publicado: (2020)

The clinicopathological significances and related signal pathways of BTG3 mRNA expression in cancers: A bioinformatics analysis
por: Zheng, Hua-Chuan, et al.
Publicado: (2022)

A conserved motif in human BTG1 and BTG2 proteins mediates interaction with the poly(A) binding protein PABPC1 to stimulate mRNA deadenylation
por: Amine, Hamza, et al.
Publicado: (2021)

BTG1 Overexpression Might Promote Invasion and Metastasis of Colorectal Cancer via Decreasing Adhesion and Inducing Epithelial–Mesenchymal Transition
por: Zhao, Shuang, et al.
Publicado: (2020)

Role of Btg2 in the Progression of a PDGF-Induced Oligodendroglioma Model
por: Appolloni, Irene, et al.
Publicado: (2012)

DSCR9/miR-21-5p axis inhibits pancreatic cancer proliferation and resistance to gemcitabine via BTG2 signaling: DSCR9/miR-21-5p/BTG2 regulates pancreatic cancer
por: Huang, Hui, et al.
Publicado: (2022)

Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression
por: Chen, Zhenyao, et al.
Publicado: (2020)

Adducin in tumorigenesis and metastasis
por: Luo, Cong, et al.
Publicado: (2017)

MiR-25-3p promotes the proliferation of triple negative breast cancer by targeting BTG2
por: Chen, Hua, et al.
Publicado: (2018)

BTG2 suppresses renal cell carcinoma progression through N6-methyladenosine
por: Qi, Fuming, et al.
Publicado: (2022)

MiR-21 Protected Cardiomyocytes against Doxorubicin-Induced Apoptosis by Targeting BTG2
por: Tong, Zhongyi, et al.
Publicado: (2015)

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
por: DeNicola, Gina M., et al.
Publicado: (2011)

BTG1 potentiates apoptosis and suppresses proliferation in renal cell carcinoma by interacting with PRMT1
por: LIU, CHUNHUI, et al.
Publicado: (2015)

The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study
por: Zheng, Hua-Chuan, et al.
Publicado: (2017)

Beyond the genome (BTG) is a (PGDB) pathway genome database: HumanCyc
por: Trupp, Miles, et al.
Publicado: (2010)

ASBEL, an ANA/BTG3 antisense transcript required for tumorigenicity of ovarian carcinoma
por: Yanagida, Satoshi, et al.
Publicado: (2013)

The Suppressive Role and Aberrent Promoter Methylation of BTG3 in the Progression of Hepatocellular Carcinoma
por: Lv, Zhenbing, et al.
Publicado: (2013)

Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma
por: Deng, Boya, et al.
Publicado: (2013)

The function of BTG3 in colorectal cancer cells and its possible signaling pathway
por: Lv, Chi, et al.
Publicado: (2017)

BTG2 as a tumor target for the treatment of luminal A breast cancer
por: Wang, Runzhi, et al.
Publicado: (2022)

Crosstalk Between ROS and Autophagy in Tumorigenesis: Understanding the Multifaceted Paradox
por: Hasan, Adria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u6ahc063n4hh5taqdh47502io3