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Toxoplasma gondii excreted‐secreted antigens suppress Foxp3 promoter activity via a SP1‐dependent mechanism

Toxoplasma gondii excreted‐secreted antigens (ESA) could result in adverse outcomes of pregnancy including abortion, stillbirth, foetal infection or teratogenesis in mice during early stage of pregnancy. Defective generation or function of regulatory T cells (Tregs) may account for those adverse pre...

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Detalles Bibliográficos
Autores principales: Chen, Jinling, Wang, Jingjing, Gao, Xuyang, Zhu, Dandan, Chen, Liuting, Duan, Yinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521278/
https://www.ncbi.nlm.nih.gov/pubmed/32729205
http://dx.doi.org/10.1111/jcmm.15703