Taurine suppresses ROS-dependent autophagy via activating Akt/mTOR signaling pathway in calcium oxalate crystals-induced renal tubular epithelial cell injury

Oxidative stress and autophagy are the key promoters of calcium oxalate (CaOx) nephrolithiasis. Taurine is an antioxidant that plays a protective role in the pathogenesis of kidney disease. Previous studies found that taurine suppressed cellular oxidative stress, and inhibited autophagy activation....

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Detalles Bibliográficos
Autores principales: Sun, Yan, Dai, Shiting, Tao, Jin, Li, Yunlong, He, Ziqi, Liu, Quan, Zhao, Jiawen, Deng, Yaoliang, Kang, Juening, Zhang, Xuepei, Yang, Sixing, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521519/
https://www.ncbi.nlm.nih.gov/pubmed/32931452
http://dx.doi.org/10.18632/aging.103730

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