Cargando…

MicroRNA-195 suppresses cell proliferation, migration and invasion in epithelial ovarian carcinoma via inhibition of the CDC42/CCND1 pathway

Epithelial ovarian carcinoma (EOC) is the most common cause of gynecological cancer mortality, and poses a threat to women. MicroRNA-195 (miR-195) has been reported to induce apoptosis of human OVCAR-3 cells by inhibiting the VEGFR2/AKT pathway. However, the role of miR-195 in EOC remains unknown. A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Xiaoying, Jia, Qingqing, Yuan, Jieling, Shi, Xiangrong, Guo, Huihui, Gao, Jiefang, Guo, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521559/ https://www.ncbi.nlm.nih.gov/pubmed/32901852 http://dx.doi.org/10.3892/ijmm.2020.4716

Ejemplares similares

CDC42EP3 promotes glioma progression via regulation of CCND1
por: Yang, Zhigang, et al.
Publicado: (2022)

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42
por: Gu, Gengshi, et al.
Publicado: (2018)

MicroRNA profiling identifies MiR-195 suppresses osteosarcoma cell metastasis by targeting CCND1
por: Han, Kang, et al.
Publicado: (2015)

MicroRNA-224 Suppresses Colorectal Cancer Cell Migration by Targeting Cdc42
por: Ke, Tao-Wei, et al.
Publicado: (2014)

CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis
por: Walck-Shannon, Elise, et al.
Publicado: (2016)

Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways
por: Pi, Jingjiang, et al.
Publicado: (2018)

Distinct predictive performance of Rac1 and Cdc42 in cell migration
por: Yamao, Masataka, et al.
Publicado: (2015)

MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1
por: Mo, Jianwen, et al.
Publicado: (2016)

Regulation and functional significance of CDC42 alternative splicing in ovarian cancer
por: He, Xiaolong, et al.
Publicado: (2015)

The Borg family of Cdc42 effector proteins Cdc42EP1–5
por: Farrugia, Aaron J., et al.
Publicado: (2016)

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
por: Farrugia, Aaron J., et al.
Publicado: (2016)

PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling
por: Deevi, R, et al.
Publicado: (2011)

Cdc42 regulates cytokine expression and trafficking in bronchial epithelial cells
por: Shouib, Rowayna, et al.
Publicado: (2022)

CDC42EP3 promotes colorectal cancer through regulating cell proliferation, cell apoptosis and cell migration
por: Feng, Qiang, et al.
Publicado: (2021)

Cdc42 turns the spindle
por: Leslie, Mitch
Publicado: (2008)

The first buds of Cdc42
por: Short, Ben
Publicado: (2015)

MicroRNA-195-5p is associated with cell proliferation, migration and invasion in prostate cancer and targets MIB1
por: Chen, Bin, et al.
Publicado: (2021)

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation
por: Kho, Mary, et al.
Publicado: (2019)

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42
por: Block, Jennifer, et al.
Publicado: (2012)

p16 Stimulates CDC42-Dependent Migration of Hepatocellular Carcinoma Cells
por: Chen, Ya-Wen, et al.
Publicado: (2013)

FBXO43 increases CCND1 stability to promote hepatocellular carcinoma cell proliferation and migration
por: Li, Chun-Ming, et al.
Publicado: (2023)

MicroRNA-466 inhibits osteosarcoma cell proliferation and induces apoptosis by targeting CCND1
por: Cao, Wei, et al.
Publicado: (2018)

MicroRNA-195-5p suppresses the proliferation, migration, invasion and epithelial-mesenchymal transition of laryngeal cancer cells in vitro by targeting E2F3
por: Zhou, Min, et al.
Publicado: (2021)

Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells
por: Otani, Tetsuhisa, et al.
Publicado: (2006)

MicroRNA-195 suppresses tumor cell proliferation and metastasis by directly targeting BCOX1 in prostate carcinoma
por: Guo, Jia, et al.
Publicado: (2015)

Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor
por: Novak, Caymen M., et al.
Publicado: (2020)

CDC50A might be a novel biomarker of epithelial ovarian cancer-initiating cells
por: Yin, Jie, et al.
Publicado: (2022)

Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration
por: Bray, Kristi, et al.
Publicado: (2013)

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin
por: Reymond, Nicolas, et al.
Publicado: (2012)

Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF
por: Jiang, Xinni, et al.
Publicado: (2016)

Actin and CDC-42 contribute to nuclear migration through constricted spaces in C. elegans
por: Ho, Jamie, et al.
Publicado: (2023)

MicroRNA-628-5p inhibits cell proliferation and induces apoptosis in colorectal cancer through downregulating CCND1 expression levels
por: Guo, Fei, et al.
Publicado: (2020)

MicroRNA-610 suppresses the proliferation of human glioblastoma cells by repressing CCND2 and AKT3
por: MO, XIAOMEI, et al.
Publicado: (2016)

MiR-7 inhibited peripheral nerve injury repair by affecting neural stem cells migration and proliferation through cdc42
por: Zhou, Nan, et al.
Publicado: (2018)

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
por: Jaffe, Aron B., et al.
Publicado: (2008)

MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2
por: Yin, Yali, et al.
Publicado: (2017)

Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction
por: Gallo Castro, Daniela, et al.
Publicado: (2018)

Demethylation of miR‐195 suppresses prostate cancer cell proliferation, migration and invasion
por: Ma, Xiaokun, et al.
Publicado: (2020)

[Retracted] MicroRNA‑628‑5p inhibits cell proliferation and induces apoptosis in colorectal cancer through downregulating CCND1 expression levels
por: Guo, Fei, et al.
Publicado: (2023)

Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation
por: Herrington, Kari A., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jpssclq234q7d0keflt9jvs4dl