Cargando…

Adaptation induced by self-targeting in a type I-B CRISPR-Cas system

Haloferax volcanii is, to our knowledge, the only prokaryote known to tolerate CRISPR-Cas–mediated damage to its genome in the WT background; the resulting cleavage of the genome is repaired by homologous recombination restoring the WT version. In mutant Haloferax strains with enhanced self-targetin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stachler, Aris-Edda, Wörtz, Julia, Alkhnbashi, Omer S., Turgeman-Grott, Israela, Smith, Rachel, Allers, Thorsten, Backofen, Rolf, Gophna, Uri, Marchfelder, Anita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521656/ https://www.ncbi.nlm.nih.gov/pubmed/32723866 http://dx.doi.org/10.1074/jbc.RA120.014030

Ejemplares similares

High tolerance to self-targeting of the genome by the endogenous CRISPR-Cas system in an archaeon
por: Stachler, Aris-Edda, et al.
Publicado: (2017)

The nuts and bolts of the Haloferax CRISPR-Cas system I-B
por: Maier, Lisa-Katharina, et al.
Publicado: (2018)

Pervasive acquisition of CRISPR memory driven by inter-species mating of archaea can limit gene transfer and influence speciation
por: Turgeman-Grott, Israela, et al.
Publicado: (2018)

An archaeal Cas3 protein facilitates rapid recovery from DNA damage
por: Miezner, Guy, et al.
Publicado: (2023)

An Active Immune Defense with a Minimal CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) RNA and without the Cas6 Protein
por: Maier, Lisa-Katharina, et al.
Publicado: (2015)

Gene Repression in Haloarchaea Using the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas I-B System
por: Stachler, Aris-Edda, et al.
Publicado: (2016)

The role of Cas8 in type I CRISPR interference
por: Cass, Simon D.B., et al.
Publicado: (2015)

A Complex of Cas Proteins 5, 6, and 7 Is Required for the Biogenesis and Stability of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii
por: Brendel, Jutta, et al.
Publicado: (2014)

Cell Surface Glycosylation Is Required for Efficient Mating of Haloferax volcanii
por: Shalev, Yarden, et al.
Publicado: (2017)

Cis-regulatory evolution in prokaryotes revealed by interspecific archaeal hybrids
por: Artieri, Carlo G., et al.
Publicado: (2017)

Cas1 and Fen1 Display Equivalent Functions During Archaeal DNA Repair
por: Wörtz, Julia, et al.
Publicado: (2022)

CRISPRcasIdentifier: Machine learning for accurate identification and classification of CRISPR-Cas systems
por: Padilha, Victor A, et al.
Publicado: (2020)

Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA
por: Liao, Chunyu, et al.
Publicado: (2022)

Special focus CRISPR-Cas
por: Marchfelder, Anita
Publicado: (2013)

Comprehensive search for accessory proteins encoded with archaeal and bacterial type III CRISPR-cas gene cassettes reveals 39 new cas gene families
por: Shah, Shiraz A., et al.
Publicado: (2018)

CRISPRtracrRNA: robust approach for CRISPR tracrRNA detection
por: Mitrofanov, Alexander, et al.
Publicado: (2022)

CRISPR-Cas: In Rekordzeit von der Grundlagenforschung zur Anwendung
por: Marchfelder, Anita
Publicado: (2020)

CRISPRloci: comprehensive and accurate annotation of CRISPR–Cas systems
por: Alkhnbashi, Omer S, et al.
Publicado: (2021)

Neighboring inteins interfere with one another's homing capacity
por: Turgeman-Grott, Israela, et al.
Publicado: (2023)

CRISPRidentify: identification of CRISPR arrays using machine learning approach
por: Mitrofanov, Alexander, et al.
Publicado: (2020)

Current Bioinformatics Tools to Optimize CRISPR/Cas9 Experiments to Reduce Off-Target Effects
por: Naeem, Muhammad, et al.
Publicado: (2023)

CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems
por: Lange, Sita J., et al.
Publicado: (2013)

Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B
por: Maier, Lisa-Katharina, et al.
Publicado: (2013)

CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci
por: Alkhnbashi, Omer S., et al.
Publicado: (2014)

Structural constraints and enzymatic promiscuity in the Cas6-dependent generation of crRNAs
por: Reimann, Viktoria, et al.
Publicado: (2017)

Casboundary: automated definition of integral Cas cassettes
por: Padilha, Victor A, et al.
Publicado: (2020)

CdrS Is a Global Transcriptional Regulator Influencing Cell Division in Haloferax volcanii
por: Liao, Yan, et al.
Publicado: (2021)

CRISPR/Cas systems in archaea: What array spacers can teach us about parasitism and gene exchange in the 3rd domain of life
por: Gophna, Uri, et al.
Publicado: (2012)

No evidence of inhibition of horizontal gene transfer by CRISPR–Cas on evolutionary timescales
por: Gophna, Uri, et al.
Publicado: (2015)

A Small RNA Is Linking CRISPR–Cas and Zinc Transport
por: Märkle, Pascal, et al.
Publicado: (2021)

Revealing the small proteome of Haloferax volcanii by combining ribosome profiling and small-protein optimized mass spectrometry
por: Hadjeras, Lydia, et al.
Publicado: (2023)

CRISPR loci reveal networks of gene exchange in archaea
por: Brodt, Avital, et al.
Publicado: (2011)

Differences in homologous recombination and maintenance of heteropolyploidy between Haloferax volcanii and Haloferax mediterranei
por: Dattani, Ambika, et al.
Publicado: (2022)

Establishing Live-Cell Single-Molecule Localization Microscopy Imaging and Single-Particle Tracking in the Archaeon Haloferax volcanii
por: Turkowyd, Bartosz, et al.
Publicado: (2020)

CRISPR-Cas Systems in the Cyanobacterium Synechocystis sp. PCC6803 Exhibit Distinct Processing Pathways Involving at Least Two Cas6 and a Cmr2 Protein
por: Scholz, Ingeborg, et al.
Publicado: (2013)

CRISPR-Cas adaptation in Escherichia coli
por: Mitić, Damjan, et al.
Publicado: (2023)

RiboReport - benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria
por: Gelhausen, Rick, et al.
Publicado: (2022)

Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family
por: Hrle, Ajla, et al.
Publicado: (2014)

A Genetic Investigation of the KEOPS Complex in Halophilic Archaea
por: Naor, Adit, et al.
Publicado: (2012)

Assigning a function to a conserved archaeal metallo-β-lactamase from Haloferax volcanii
por: Fischer, Susan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_dt93399n1d982qn0oa6ngandka