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Protocol for Designing Small-Molecule-Regulated Destabilizing Domains for In Vitro Use
The use of destabilizing domains (DDs) to conditionally control the abundance of a protein of interest (POI) through a small-molecule stabilizer has gained increasing traction both in vitro and in vivo. Yet there are specific considerations for the development and accurate control of user-defined PO...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521665/ https://www.ncbi.nlm.nih.gov/pubmed/32995752 http://dx.doi.org/10.1016/j.xpro.2020.100069 |