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Mining a human transcriptome database for chemical modulators of NRF2
Nuclear factor erythroid-2 related factor 2 (NRF2) encoded by the NFE2L2 gene is a transcription factor critical for protecting cells from chemically-induced oxidative stress. We developed computational procedures to identify chemical modulators of NRF2 in a large database of human microarray data....
Autores principales: | Rooney, John P., Chorley, Brian, Hiemstra, Steven, Wink, Steven, Wang, Xuting, Bell, Douglas A., van de Water, Bob, Corton, J. Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521735/ https://www.ncbi.nlm.nih.gov/pubmed/32986742 http://dx.doi.org/10.1371/journal.pone.0239367 |
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