Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling

Tractional remodeling of collagen fibrils by fibroblasts requires long cell extensions that mediate fibril alignment. The formation of these cell extensions involves flightless I (FliI), an actin-binding protein that contains a leucine-rich-repeat (LRR), which binds R-ras and may regulate cdc42. We...

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Detalles Bibliográficos
Autores principales: Arora, P. D., Nakajima, K., Nanda, A., Plaha, A., Wilde, A., Sacks, D. B., McCulloch, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521798/
https://www.ncbi.nlm.nih.gov/pubmed/32432944
http://dx.doi.org/10.1091/mbc.E19-10-0554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521798/
https://www.ncbi.nlm.nih.gov/pubmed/32432944
http://dx.doi.org/10.1091/mbc.E19-10-0554

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