Cargando…
Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling
Tractional remodeling of collagen fibrils by fibroblasts requires long cell extensions that mediate fibril alignment. The formation of these cell extensions involves flightless I (FliI), an actin-binding protein that contains a leucine-rich-repeat (LRR), which binds R-ras and may regulate cdc42. We...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521798/ https://www.ncbi.nlm.nih.gov/pubmed/32432944 http://dx.doi.org/10.1091/mbc.E19-10-0554 |