Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics

Nuclei are often under external stress, be it during migration through tight constrictions or compressive pressure by the actin cap, and the mechanical properties of nuclei govern their subsequent deformations. Both altered mechanical properties of nuclei and abnormal nuclear morphologies are hallma...

Descripción completa

Detalles Bibliográficos
Autores principales: Hobson, Chad M., Kern, Megan, O’Brien, E. Timothy, Stephens, Andrew D., Falvo, Michael R., Superfine, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521857/
https://www.ncbi.nlm.nih.gov/pubmed/32267206
http://dx.doi.org/10.1091/mbc.E20-01-0073

Ejemplares similares

Ejemplares similares