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Mechanical stress triggers nuclear remodeling and the formation of transmembrane actin nuclear lines with associated nuclear pore complexes
Mechanical stimulation of fibroblasts induces changes in the actin cytoskeleton including stress fiber (SF) reinforcement and realignment. Here we characterize the nuclear response to mechanical stimulation (uniaxial cyclic stretch). Using fluorescence microscopy and quantitative image analysis we f...
Autores principales: | Hoffman, Laura M., Smith, Mark A., Jensen, Christopher C., Yoshigi, Masaaki, Blankman, Elizabeth, Ullman, Katharine S., Beckerle, Mary C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521858/ https://www.ncbi.nlm.nih.gov/pubmed/31967947 http://dx.doi.org/10.1091/mbc.E19-01-0027 |
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