TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis

Wnt signaling through the Frizzled (FZD) family of serpentine receptors is essential for embryogenesis and homeostasis, and stringent control of the FZD protein level is critical for stem cell regulation. Through CRISPR/Cas9 genome-wide screening in human cells, we identified TMEM79/MATTRIN, an orph...

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Detalles Bibliográficos
Autores principales: Chen, Maorong, Amado, Nathalia, Tan, Jieqiong, Reis, Alice, Ge, Mengxu, Abreu, Jose Garcia, He, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521923/
https://www.ncbi.nlm.nih.gov/pubmed/32924931
http://dx.doi.org/10.7554/eLife.56793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7521923/
https://www.ncbi.nlm.nih.gov/pubmed/32924931
http://dx.doi.org/10.7554/eLife.56793

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