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Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome

Mouse models of Down syndrome (DS) have been invaluable tools for advancing knowledge of the underlying mechanisms of intellectual disability in people with DS. The Ts(17(16))65Dn (Ts65Dn) mouse is one of the most commonly used models as it recapitulates many of the phenotypes seen in individuals wi...

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Detalles Bibliográficos
Autores principales: Shaw, Patricia R., Klein, Jenny A., Aziz, Nadine M., Haydar, Tarik F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522024/
https://www.ncbi.nlm.nih.gov/pubmed/32817053
http://dx.doi.org/10.1242/dmm.046243

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