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Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness
Glucocorticoids are routinely used in the clinic as anti-inflammatory and immunosuppressive agents as well as adjuvants during cancer treatment to mitigate the undesirable side effects of chemotherapy. However, recent studies have indicated that glucocorticoids may negatively impact the efficacy of...
Autores principales: | Karvonen, Hanna, Arjama, Mariliina, Kaleva, Laura, Niininen, Wilhelmiina, Barker, Harlan, Koivisto-Korander, Riitta, Tapper, Johanna, Pakarinen, Päivi, Lassus, Heini, Loukovaara, Mikko, Bützow, Ralf, Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522257/ https://www.ncbi.nlm.nih.gov/pubmed/32989221 http://dx.doi.org/10.1038/s41419-020-03009-4 |
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