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The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling
Determining subclinical Brain stroke (BS) risk factors may allow for early and more operative BS prevention measures to find the main risk factors and moderating effects of survival in patients with BS. In this prospective study, a total of 332 patients were recruited from 2004 up to 2018. Cox'...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522261/ https://www.ncbi.nlm.nih.gov/pubmed/32985561 http://dx.doi.org/10.1038/s41598-020-72814-w |
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author | Someeh, Nasrin Shamshirgaran, Seyed Morteza Farzipoor, Farshid Asghari-Jafarabadi, Mohammad |
author_facet | Someeh, Nasrin Shamshirgaran, Seyed Morteza Farzipoor, Farshid Asghari-Jafarabadi, Mohammad |
author_sort | Someeh, Nasrin |
collection | PubMed |
description | Determining subclinical Brain stroke (BS) risk factors may allow for early and more operative BS prevention measures to find the main risk factors and moderating effects of survival in patients with BS. In this prospective study, a total of 332 patients were recruited from 2004 up to 2018. Cox's proportional hazard regressions were used to analyze the predictors of survival and the moderating effect by introducing the interaction effects. The survival probability 1-, 5- and 10-year death rates were 0.254, 0.053, and 0. 023, respectively. The most important risk factors for predicting BS were age category, sex, history of blood pressure, history of diabetes, history of hyperlipoproteinemia, oral contraceptive pill, hemorrhagic cerebrovascular accident. Interestingly, the age category and education level, smoking and using oral contraceptive pill moderates the relationship between the history of cerebrovascular accident, history of heart disease, and history of blood pressure with the hazard of BS, respectively. Instead of considerable advances in the treatment of the patient with BS, effective BS prevention remains the best means for dropping the BS load regarding the related factors found in this study. |
format | Online Article Text |
id | pubmed-7522261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75222612020-09-29 The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling Someeh, Nasrin Shamshirgaran, Seyed Morteza Farzipoor, Farshid Asghari-Jafarabadi, Mohammad Sci Rep Article Determining subclinical Brain stroke (BS) risk factors may allow for early and more operative BS prevention measures to find the main risk factors and moderating effects of survival in patients with BS. In this prospective study, a total of 332 patients were recruited from 2004 up to 2018. Cox's proportional hazard regressions were used to analyze the predictors of survival and the moderating effect by introducing the interaction effects. The survival probability 1-, 5- and 10-year death rates were 0.254, 0.053, and 0. 023, respectively. The most important risk factors for predicting BS were age category, sex, history of blood pressure, history of diabetes, history of hyperlipoproteinemia, oral contraceptive pill, hemorrhagic cerebrovascular accident. Interestingly, the age category and education level, smoking and using oral contraceptive pill moderates the relationship between the history of cerebrovascular accident, history of heart disease, and history of blood pressure with the hazard of BS, respectively. Instead of considerable advances in the treatment of the patient with BS, effective BS prevention remains the best means for dropping the BS load regarding the related factors found in this study. Nature Publishing Group UK 2020-09-28 /pmc/articles/PMC7522261/ /pubmed/32985561 http://dx.doi.org/10.1038/s41598-020-72814-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Someeh, Nasrin Shamshirgaran, Seyed Morteza Farzipoor, Farshid Asghari-Jafarabadi, Mohammad The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title | The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title_full | The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title_fullStr | The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title_full_unstemmed | The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title_short | The moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
title_sort | moderating role of underlying predictors of survival in patients with brain stroke: a statistical modeling |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522261/ https://www.ncbi.nlm.nih.gov/pubmed/32985561 http://dx.doi.org/10.1038/s41598-020-72814-w |
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