Cargando…
Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes
Type 1 diabetes (T1D) is a chronic disease caused by the selective destruction of the insulin-producing pancreatic beta cells by infiltrating immune cells. We presently evaluated the transcriptomic signature observed in beta cells in early T1D and compared it with the signatures observed following i...
Autores principales: | Colli, Maikel L., Szymczak, Florian, Eizirik, Decio L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522353/ https://www.ncbi.nlm.nih.gov/pubmed/33042023 http://dx.doi.org/10.3389/fendo.2020.568446 |
Ejemplares similares
-
ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation
por: Szymczak, Florian, et al.
Publicado: (2022) -
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA
por: Colli, Maikel L., et al.
Publicado: (2010) -
From Pancreatic β-Cell Gene Networks to Novel Therapies for Type 1 Diabetes
por: Eizirik, Decio L., et al.
Publicado: (2021) -
ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes
por: Brozzi, Flora, et al.
Publicado: (2016) -
SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature
por: Fignani, Daniela, et al.
Publicado: (2020)