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Inguinal lymph node metastasis of bladder carcinoma after radical cystectomy: A case report and review of literature

INTRODUCTION: Lymph node metastasis in bladder cancer (BC) is common and has been associated with a very poor prognosis. Bc rarely metastasizes to inguinal lymph nodes. PRESENTATION OF CASE: We reported an unusual case of right inguinal lymph node metastasis of transitional cell carcinoma of the bla...

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Detalles Bibliográficos
Autores principales: Moussa, Mohamad, Chakra, Mohamed Abou, Papatsoris, Athanasios, Dellis, Athanasios, Saad, Wajih, Chahine, Nazih Bou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522444/
https://www.ncbi.nlm.nih.gov/pubmed/32992094
http://dx.doi.org/10.1016/j.ijscr.2020.09.068
Descripción
Sumario:INTRODUCTION: Lymph node metastasis in bladder cancer (BC) is common and has been associated with a very poor prognosis. Bc rarely metastasizes to inguinal lymph nodes. PRESENTATION OF CASE: We reported an unusual case of right inguinal lymph node metastasis of transitional cell carcinoma of the bladder. Metastasis occurred 9 months after radical cystectomy for BC. The patient refused chemotherapy and underwent only surgical excision of lymph nodes without any adjuvant therapy. During a follow-up period of 3 years, the patient still having complete remission. DISCUSSION: Multiple studies showed an improved clinical outcome with adjuvant chemotherapy for pathological node-positive patients with BC. Long-term survival could be achieved for some patients with limited lymph node metastasis who underwent metastasectomy. Some studies supported the benefit of surgical consolidation after a good response to systemic chemotherapy. The best management plan for clinically node-positive BC is not established yet. CONCLUSION: There is little evidence on which to base the management of inguinal lymph node metastasis from BC. Metastasectomy could be an option with good outcomes.