Cargando…

Neuroanatomical and Microglial Alterations in the Striatum of Levodopa-Treated, Dyskinetic Hemi-Parkinsonian Rats

Dyskinesia associated with chronic levodopa treatment in Parkinson’s disease is associated with maladaptive striatal plasticity. The objective of this study was to examine whether macroscale structural changes, as captured by magnetic resonance imaging (MRI) accompany this plasticity and to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fletcher, Edward J. R., Finlay, Clare J., Amor Lopez, Ana, Crum, William R., Vernon, Anthony C., Duty, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522511/ https://www.ncbi.nlm.nih.gov/pubmed/33041762 http://dx.doi.org/10.3389/fnins.2020.567222

Ejemplares similares

Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
por: Cantuti-Castelvetri, Ippolita, et al.
Publicado: (2010)

Anti-dyskinetic efficacy of 5-HT3 receptor antagonist in the hemi-parkinsonian rat model
por: Aboulghasemi, Nazanin, et al.
Publicado: (2018)

What Mechanisms Are Responsible for the Reuptake of Levodopa-Derived Dopamine in Parkinsonian Striatum?
por: Nishijima, Haruo, et al.
Publicado: (2016)

Brain Morphometry and the Neurobiology of Levodopa-Induced Dyskinesias: Current Knowledge and Future Potential for Translational Pre-Clinical Neuroimaging Studies
por: Finlay, Clare J., et al.
Publicado: (2014)

Parkinsonian Symptoms, Not Dyskinesia, Negatively Affect Active Life Participation of Dyskinetic Patients with Parkinson’s Disease
por: Goubault, Etienne, et al.
Publicado: (2020)

Verbal adynamia in parkinsonian syndromes: behavioral correlates and neuroanatomical substrate
por: Magdalinou, Nadia K, et al.
Publicado: (2018)

Systematic Evaluation of DBS Parameters in the Hemi-Parkinsonian Rat Model
por: Mottaghi, Soheil, et al.
Publicado: (2020)

Elevated Homocysteine by Levodopa Is Detrimental to Neurogenesis in Parkinsonian Model
por: Shin, Jin Young, et al.
Publicado: (2012)

Dopamine D1 receptor signalling in dyskinetic Parkinsonian rats revealed by fiber photometry using FRET-based biosensors
por: Jones-Tabah, Jace, et al.
Publicado: (2020)

Repetitive transcranial magnetic stimulation (rTMS) improves behavioral and biochemical deficits in levodopa-induced dyskinetic rats model
por: Ba, Maowen, et al.
Publicado: (2016)

Biochemical Changes Induced by Embryonic Substantia Nigra Transplanted to the Striatum of Parkinsonian Monkeys
por: Elsworth, J. D., et al.
Publicado: (1992)

Pharmacokinetics of Levodopa and 3-O-Methyldopa in Parkinsonian Patients Treated with Levodopa and Ropinirole and in Patients with Motor Complications
por: Adamiak-Giera, Urszula, et al.
Publicado: (2021)

Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic
por: Mercado, Natosha M, et al.
Publicado: (2016)

Altered Resting-State Functional Connectivity of the Striatum in Parkinson's Disease after Levodopa Administration
por: Yang, Wanqun, et al.
Publicado: (2016)

The selective 5-HT(1A) receptor agonist, NLX-112, exerts anti-dyskinetic and anti-parkinsonian-like effects in MPTP-treated marmosets
por: Fisher, Ria, et al.
Publicado: (2020)

Antidyskinetic Treatment with MTEP Affects Multiple Molecular Pathways in the Parkinsonian Striatum
por: Lin, Jing-ya, et al.
Publicado: (2017)

Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy
por: Qin, Yun, et al.
Publicado: (2018)

Adaptive deep brain stimulation controls levodopa‐induced side effects in Parkinsonian patients
por: Rosa, Manuela, et al.
Publicado: (2017)

Levodopa-Responsive Parkinsonian Syndrome Secondary to a Compressive Craniopharyngioma: A Case Report
por: Rodriguez, Wilson, et al.
Publicado: (2023)

Perioperative Use of Intravenous Levodopa as an Anti‐Parkinsonian Drug: A Propensity Score Analysis
por: Kodama, Satoshi, et al.
Publicado: (2023)

Transplantation of Melanocytes Obtained from the Skin Ameliorates Apomorphine-Induced Abnormal Behavior in Rodent Hemi-Parkinsonian Models
por: Asanuma, Masato, et al.
Publicado: (2013)

Development of a controlled-release anti-parkinsonian nanodelivery system using levodopa as the active agent
por: Kura, Aminu Umar, et al.
Publicado: (2013)

Attempted Suicide in a Parkinsonian Patient Treated with DBS of the VIM and High Dose Carbidopa-Levodopa
por: Ayobello, Ayotunde, et al.
Publicado: (2019)

Neuroprotective Effect of Thymoquinone, the Nigella Sativa Bioactive Compound, in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Rat Model
por: Sedaghat, Reza, et al.
Publicado: (2014)

The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial
por: Bonouvrié, Laura A., et al.
Publicado: (2019)

Hemi-Hyperkinesis
por: Rostowski, J., et al.
Publicado: (1950)

Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2005)

Neuroradiological and Neurophysiological Characteristics of Patients With Dyskinetic Cerebral Palsy
por: Park, Byung-Hyun, et al.
Publicado: (2014)

Rare Form of Dyskinetic Movements Associated with Alcohol Withdrawal
por: Prakash, Sathya, et al.
Publicado: (2016)

Histological Correlates of Neuroanatomical Changes in a Rat Model of Levodopa-Induced Dyskinesia Based on Voxel-Based Morphometry
por: Zhang, Xiaoqian, et al.
Publicado: (2021)

Correction: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition
por: Croisier, Emilie, et al.
Publicado: (2006)

Use of the Dyskinesia Impairment Scale in non‐ambulatory dyskinetic cerebral palsy
por: Haberfehlner, Helga, et al.
Publicado: (2019)

Striatal Glutamate Release in l-DOPA-Induced Dyskinetic Animals
por: Nevalainen, Nina, et al.
Publicado: (2013)

Correction: Neuroradiological and Neurophysiological Characteristics of Patients With Dyskinetic Cerebral Palsy
por: Park, Byung-Hyun, et al.
Publicado: (2015)

Aberrant Interhemispheric Functional Organization in Children with Dyskinetic Cerebral Palsy
por: Qin, Yun, et al.
Publicado: (2019)

Cardiac tyrosine hydroxylase activation and MB-COMT in dyskinetic monkeys
por: Cuenca-Bermejo, Lorena, et al.
Publicado: (2021)

Dopaminergic-Like Neurons Derived from Oral Mucosa Stem Cells by Developmental Cues Improve Symptoms in the Hemi-Parkinsonian Rat Model
por: Ganz, Javier, et al.
Publicado: (2014)

Gait Analysis of Old Individuals with Mild Parkinsonian Signs and Those Individuals’ Gait Performance Benefits Little from Levodopa
por: Wu, Zhuang, et al.
Publicado: (2021)

Instrumented assessment of motor function in dyskinetic cerebral palsy: a systematic review
por: Haberfehlner, Helga, et al.
Publicado: (2020)

Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson’s Disease
por: Perez-Bouza, Alberto, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a1knm1o4cm0sdovi1948lloqcf