Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families

PURPOSE: There is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19). PATIENTS AND METHODS: Three medical staff...

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Detalles Bibliográficos
Autores principales: Zhang, Xian, Chen, Liting, Wei, Jia, Zhou, Jianfeng, Cao, Yang, Wang, Gaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522516/
https://www.ncbi.nlm.nih.gov/pubmed/33061473
http://dx.doi.org/10.2147/IDR.S261304
Descripción
Sumario:PURPOSE: There is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19). PATIENTS AND METHODS: Three medical staff who were asymptomatic were diagnosed with coronavirus disease 2019 by serological tests. Their close contacts were systematically evaluated based on COVID-19-related symptoms, nucleic acid tests, serological tests, and chest computed tomography (CT) as needed to determine if they were infected by SARS-CoV-2. RESULTS: None of the staff’s close contacts, including 10 family members, were infected by the indexes, even though no protective measures were taken. CONCLUSION: The infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low.

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