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First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa

Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there...

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Detalles Bibliográficos
Autores principales: Nlandu, Yannick M., Makulo, Jean-Robert R., Pakasa, Nestor M., Sumaili, Ernest K., Nkondi, Clarisse N., Bukabau, Justine B., Beya, François K., Nseka, Nazaire M., Lepira, François B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522604/
https://www.ncbi.nlm.nih.gov/pubmed/33005463
http://dx.doi.org/10.1155/2020/8820713
Descripción
Sumario:Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria.