Cargando…

First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa

Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there...

Descripción completa

Detalles Bibliográficos
Autores principales: Nlandu, Yannick M., Makulo, Jean-Robert R., Pakasa, Nestor M., Sumaili, Ernest K., Nkondi, Clarisse N., Bukabau, Justine B., Beya, François K., Nseka, Nazaire M., Lepira, François B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522604/
https://www.ncbi.nlm.nih.gov/pubmed/33005463
http://dx.doi.org/10.1155/2020/8820713
_version_ 1783588219747565568
author Nlandu, Yannick M.
Makulo, Jean-Robert R.
Pakasa, Nestor M.
Sumaili, Ernest K.
Nkondi, Clarisse N.
Bukabau, Justine B.
Beya, François K.
Nseka, Nazaire M.
Lepira, François B.
author_facet Nlandu, Yannick M.
Makulo, Jean-Robert R.
Pakasa, Nestor M.
Sumaili, Ernest K.
Nkondi, Clarisse N.
Bukabau, Justine B.
Beya, François K.
Nseka, Nazaire M.
Lepira, François B.
author_sort Nlandu, Yannick M.
collection PubMed
description Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria.
format Online
Article
Text
id pubmed-7522604
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-75226042020-09-30 First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa Nlandu, Yannick M. Makulo, Jean-Robert R. Pakasa, Nestor M. Sumaili, Ernest K. Nkondi, Clarisse N. Bukabau, Justine B. Beya, François K. Nseka, Nazaire M. Lepira, François B. Case Rep Nephrol Case Report Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria. Hindawi 2020-09-28 /pmc/articles/PMC7522604/ /pubmed/33005463 http://dx.doi.org/10.1155/2020/8820713 Text en Copyright © 2020 Yannick M. Nlandu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nlandu, Yannick M.
Makulo, Jean-Robert R.
Pakasa, Nestor M.
Sumaili, Ernest K.
Nkondi, Clarisse N.
Bukabau, Justine B.
Beya, François K.
Nseka, Nazaire M.
Lepira, François B.
First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title_full First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title_fullStr First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title_full_unstemmed First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title_short First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
title_sort first case of covid-19-associated collapsing glomerulopathy in sub-saharan africa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522604/
https://www.ncbi.nlm.nih.gov/pubmed/33005463
http://dx.doi.org/10.1155/2020/8820713
work_keys_str_mv AT nlanduyannickm firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT makulojeanrobertr firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT pakasanestorm firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT sumailiernestk firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT nkondiclarissen firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT bukabaujustineb firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT beyafrancoisk firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT nsekanazairem firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica
AT lepirafrancoisb firstcaseofcovid19associatedcollapsingglomerulopathyinsubsaharanafrica