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Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis

AIM: This study investigated the effects of antitox and Vitamin E-selenium on meat quality and safety in rabbits after experimental 1,1-dimethylhydrazine (1,1-DMH) toxicosis. MATERIALS AND METHODS: Experimental groups of rabbits weighing 1.5-2.5 kg each were kept in a vivarium under same controlled...

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Autores principales: Maikanov, Balgabay S., Zabolotnykh, Mikhail V., Auteleyeva, Laura T., Seidenova, Symbat P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522960/
https://www.ncbi.nlm.nih.gov/pubmed/33061228
http://dx.doi.org/10.14202/vetworld.2020.1567-1572
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author Maikanov, Balgabay S.
Zabolotnykh, Mikhail V.
Auteleyeva, Laura T.
Seidenova, Symbat P.
author_facet Maikanov, Balgabay S.
Zabolotnykh, Mikhail V.
Auteleyeva, Laura T.
Seidenova, Symbat P.
author_sort Maikanov, Balgabay S.
collection PubMed
description AIM: This study investigated the effects of antitox and Vitamin E-selenium on meat quality and safety in rabbits after experimental 1,1-dimethylhydrazine (1,1-DMH) toxicosis. MATERIALS AND METHODS: Experimental groups of rabbits weighing 1.5-2.5 kg each were kept in a vivarium under same controlled conditions (temperature 16-21°C, humidity 60-80%, 12/12 h light/dark cycle, noise level <85 dB) with free access to standard food containing 22.0% protein, 4.5% fat, and 4% fiber. The effect of a detoxifying mixture of antitox and Vitamin E-selenium on safety indicators (residual amount of 1,1-DMH) and quality indicators pre- and post-detoxification of the rabbits from 1,1-DMH was determined. RESULTS: After detoxification, the residual 1,1-DMH level decreased in all organs and tissues to <0.1 mg/kg. The nutritional value of meat increased by improving organoleptic, physical, and chemical parameters and the amino acid composition of protein. CONCLUSION: The antitox+Vitamin E-selenium detoxifying mixture significantly decreases the residual 1,1-DMH level in organs and tissues of animals and increases the nutritional value of rabbit meat in subacute poisoning. The detoxifying mixture can also be used on animals grazing in territories adjacent to Proton-M launch sites for preventive and therapeutic purposes.
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spelling pubmed-75229602020-10-14 Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis Maikanov, Balgabay S. Zabolotnykh, Mikhail V. Auteleyeva, Laura T. Seidenova, Symbat P. Vet World Research Article AIM: This study investigated the effects of antitox and Vitamin E-selenium on meat quality and safety in rabbits after experimental 1,1-dimethylhydrazine (1,1-DMH) toxicosis. MATERIALS AND METHODS: Experimental groups of rabbits weighing 1.5-2.5 kg each were kept in a vivarium under same controlled conditions (temperature 16-21°C, humidity 60-80%, 12/12 h light/dark cycle, noise level <85 dB) with free access to standard food containing 22.0% protein, 4.5% fat, and 4% fiber. The effect of a detoxifying mixture of antitox and Vitamin E-selenium on safety indicators (residual amount of 1,1-DMH) and quality indicators pre- and post-detoxification of the rabbits from 1,1-DMH was determined. RESULTS: After detoxification, the residual 1,1-DMH level decreased in all organs and tissues to <0.1 mg/kg. The nutritional value of meat increased by improving organoleptic, physical, and chemical parameters and the amino acid composition of protein. CONCLUSION: The antitox+Vitamin E-selenium detoxifying mixture significantly decreases the residual 1,1-DMH level in organs and tissues of animals and increases the nutritional value of rabbit meat in subacute poisoning. The detoxifying mixture can also be used on animals grazing in territories adjacent to Proton-M launch sites for preventive and therapeutic purposes. Veterinary World 2020-08 2020-08-12 /pmc/articles/PMC7522960/ /pubmed/33061228 http://dx.doi.org/10.14202/vetworld.2020.1567-1572 Text en Copyright: © Maikanov, et al. http://creativecommons.org/licenses/by/4.0 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Maikanov, Balgabay S.
Zabolotnykh, Mikhail V.
Auteleyeva, Laura T.
Seidenova, Symbat P.
Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title_full Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title_fullStr Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title_full_unstemmed Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title_short Influence of antitox and Vitamin E-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
title_sort influence of antitox and vitamin e-selenium on meat quality and safety in rabbits after 1,1-experimental dimethylhydrazine toxicosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522960/
https://www.ncbi.nlm.nih.gov/pubmed/33061228
http://dx.doi.org/10.14202/vetworld.2020.1567-1572
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