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FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids
Humans have undergone intense evolutionary selection to optimize their capacity to generate necessary quantities of long chain (LC-) polyunsaturated fatty acid (PUFA)-containing lipids. To better understand the impact of genetic variation within a locus of three FADS genes (FADS1, FADS2, and FADS3)...
Autores principales: | Reynolds, Lindsay M., Dutta, Rahul, Seeds, Michael C., Lake, Kirsten N., Hallmark, Brian, Mathias, Rasika A., Howard, Timothy D., Chilton, Floyd H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522985/ https://www.ncbi.nlm.nih.gov/pubmed/32985521 http://dx.doi.org/10.1038/s41598-020-71948-1 |
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